Xiaoqian LIU (Ph.D)

School of Pharmaceutical Engineering & Life Science, Changzhou University

Education：

2006/08 - 2010/08, National University of Singapore, Ph.D in organic and medicinal chemistry

2002/08 - 2006/08, Soochow University, Bachelor in chemistry

Working Experience:

2014/09 - now，Changzhou University,

2011/06 - 2014/08, Singapore Polytechnic, Center for biomedical and life science

Fundings：

1.Department of Education in Jiangsu Province，SCZ1422100002,“Development and application of asymmetrical squaraine dyes”，principal investigator, 2014-now.

2.Start-up funding in Changzhou University, principal investigator, 2014-now.

3.Ministry of Education, Singapore, MOE 2012-TIF-1-T-05, “Development of near infrared probe for studying anti-malaria drug resistant”, 2012-2014, principal investigator.

4.Singapore Polytechnic research funding, Idea Farm, “Screening lead compounds and bio-imaging for EV-71 virus”, 2011-2013，principal investigator.

5.Ministry of Education, Singapore, MOE 2010-IF-022, “Development of near infrared dyes for organic solar cells”, 2010-2012, major participator.

6.Singapore biomedical research council, BMRC R-143-000-349-305, “Synthesis and biological evaluation of natural antibiotic Varacin C”, 2009-2011, major participator.

7.Ministry of Education, Singapore, R-143-000-362-112, “Asymmetrical cyclization reaction for natural alkaloid catalysis”, 2006-2008, major participator.

Selective Publications：

1.Xiaoqian Liu, Bokun Cho, Li-Yan Chan, Wei Lek Kwan and Chi-Lik Ken Lee*. Development of asymmetrical near infrared squaraines with large stokes shift. RSC Adv. 2015, 5, 106868.

2.Swee Ling Lam, Xiaoqian Liu, Fangli Zhao, Chi-Lik Ken Lee and Wei Lek Kwan*. Manipulating open-circuit voltage in organic photovoltaic device via a phenyl-alkyl side chain. Chemical Communications, 2013, 4543.

3.Xiaoqian Liu, Enhancement of Nucleophilic Aromatic Substitutions by the Synergistic Effects of Microcavitation and Continuous-Flow Chemistry. Journal of Flow Chemistry, 2013, 3(4), 114.

4.Xiaoqian Liu. A combined use of ultrasound and flow chemistry: An enhanced methodology in organic synthesis. Asian flow chemistry, Suntec City, Singapore, Oct 25-26, 2012.

5.Tan, Li-Min; Sem, Zhi-Yu; Chong, Wei-Yuan; Xiaoqian Liu,; Hendra; Kwan, Wei Lek; Lee, Chi-Lik Ken. Continuous flow Sonogashira C-C coupling using a heterogeneous palladium-copper dual reactor. Org Lett, 2013,15(1), 65-67.

6.Xiaoqian Liu. A combined use of ultrasound and flow chemistry: An enhanced methodology in organic synthesis. Asian flow chemistry, 2012/10/25-2012/10/26.

7.Xiaoqian Liu, Yixin Lu*. Asymmetric Synthesis of 2-Aryl-2, 3-dihydro-4-quinolones via Bifunctional thiourea-mediated intramolecular cyclization. Org. Lett. 2011, 23, 5592.

8.Xiaoqian Liu, Yixin Lu*. Bifunctional thiourea-promoted cascade aza-Michael-Henry-dehydration reactions: asymmetric preparation of 3-nitro-1, 2-dihydroquinolines Org. Bio. Chem. 2010, 8, 4063.

9.Xiaoqian Liu, Jiahui Zheng, Qing Yuan, Yoon-Joo Shin, Daekyu Sun, Yixin Lu*. Thiol-dependent DNA cleavage by aminomethylated Beaucage’s reagent. Org. Bio. Chem. 2010, 8, 1293.