Contact:
School of Pharmaceutical Engineering & Life Science
Changzhou University
Changzhou, Jiangsu 213164, China
Email: zhaoshuai@cczu.edu.cn
Research Interests:
Organocatalysis, Asymmetric synthesis of small molecules with important biological activities
Educational background:
2015.6- School of Pharmaceutical Engineering & Life Science, Changzhou University
2010.9-2015.6 Ph.D. (Major: Organic Chemistry) College of Chemistry and Chemical Engineering, Lanzhou University
2006.9-2010.6 B.Sc. (Major: Chemistry (Basic Theory Class)) College of Chemistry and Chemical Engineering, Lanzhou University
Fundings:
1. The Fundamental Research Funds for the Central Universities (lzujbky-2014-242), Synthesis of spirooxindole by Organocatalysis, 2014/1-2015/6, PI.
2. National Science Foundation of China project (grant No. 21602018), Asymmetric α-alkylation of unactivated esters catalyzed by chiral quaternary ammonium fluoride, 2017/1 – 2019/1, PI
Publications:
1.Shuai Zhao, Yuan-Yuan Zhao, Jun-Bing Lin, Yong-Ming Liang, Peng-Fei Xu*. Organocatalyzed Asymmetric Vinylogous Allylic-Allylic Alkylation of Morita-Baylis-Hillman Carbonates with Olefinic Azlactones: Facile Access to Chiral Multifunctional α-Amino Acid Derivatives. Org. Lett.2015, 17, 3206.
2.Shuai Zhao, Jun-Bing Lin, Yuan-Yuan Zhao, Yong-Ming Liang, Peng-Fei Xu*. Hydrogen-bond-directed formal [5 + 1] annulations of oxindoles with ester-linked bisenones: facile access to chiral spirooxindole δ-Lactones. Org. Lett.2014, 16, 1802.
3.Yuan-Yuan Zhao, Shuai Zhao, Ji-Kang Xie, Xiu-Qin Hu, Peng-Fei Xu*. Synthesis of Spirocyclic Oxindole Dihydrothiophenes by DBUCatalyzed [3 + 2] Annulation of Morita−Baylis−Hillman Carbonates with Isothiocyanates. J. Org. Chem.2016, 81, 10532.
4. Ting Xie, Yu Xiao, Shuai Zhao, Xiu-Qin Hu, Peng-Fei Xu*. Catalyst-Free Chemoselective Synthesis of 3,4-Dihydroquinazoline-2-thiones and 2‑Imino[1,3]benzothiazines. J. Org. Chem.2016, 81, 10499.
5. Wang, Qinting Zhao, Shuai Jin, Lei Chen, Xin. Synthesis of Fmoc-protected (S)-3,5-Dibromophenylalanine in the Presence of a Phase Transfer Catalyst or a Chiral Catalyst, Chin. J. Org. Chem.2016, 36, 2242 ( In Chinese).